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In Vivo Importance of Actin Nucleotide Exchange Catalyzed by Profilin
The actin monomer-binding protein, profilin, influences the dynamics of actin filaments in vitro by suppressing nucleation, enhancing nucleotide exchange on actin, and promoting barbed-end assembly. Profilin may also link signaling pathways to actin cytoskeleton organization by binding to the phosph...
Autores principales: | Wolven, Amy K., Belmont, Lisa D., Mahoney, Nicole M., Almo, Steven C., Drubin, David G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175289/ https://www.ncbi.nlm.nih.gov/pubmed/10953013 |
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