Human DNA mismatch repair: coupling of mismatch recognition to strand-specific excision

Eukaryotic mismatch-repair (MMR) proteins MutSα and MutLα couple recognition of base mismatches to strand-specific excision, initiated in vivo at growing 3′ ends and 5′ Okazaki-fragment ends or, in human nuclear extracts, at nicks in exogenous circular substrates. We addressed five biochemical quest...

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Detalles Bibliográficos
Autores principales: Wang, Huixian, Hays, John B.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175295/
https://www.ncbi.nlm.nih.gov/pubmed/17921148
http://dx.doi.org/10.1093/nar/gkm734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175295/
https://www.ncbi.nlm.nih.gov/pubmed/17921148
http://dx.doi.org/10.1093/nar/gkm734

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