Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification

FOXO3a is a transcription factor of the FOXO family. The FOXO proteins participate in multiple signaling pathways, and their transcriptional activity is regulated by several post-translational mechanisms, including phosphorylation, acetylation and ubiquitination. Because these post-translational mod...

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Detalles Bibliográficos
Autores principales: Tsai, Kuang-Lei, Sun, Yuh-Ju, Huang, Cheng-Yang, Yang, Jer-Yen, Hung, Mien-Chie, Hsiao, Chwan-Deng
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175300/
https://www.ncbi.nlm.nih.gov/pubmed/17940099
http://dx.doi.org/10.1093/nar/gkm703

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