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Conserved amino acids in each subunit of the heteroligomeric tRNA m(1)A58 Mtase from Saccharomyces cerevisiae contribute to tRNA binding
In Saccharomyces cerevisiae, a two-subunit methyltransferase (Mtase) encoded by the essential genes TRM6 and TRM61 is responsible for the formation of 1-methyladenosine, a modified nucleoside found at position 58 in tRNA that is critical for the stability of [Formula: see text]. The crystal structur...
Autores principales: | Ozanick, Sarah G., Bujnicki, Janusz M., Sem, Daniel S., Anderson, James T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175304/ https://www.ncbi.nlm.nih.gov/pubmed/17932071 http://dx.doi.org/10.1093/nar/gkm574 |
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