CG dinucleotide clustering is a species-specific property of the genome

Cytosines at cytosine-guanine (CG) dinucleotides are the near-exclusive target of DNA methyltransferases in mammalian genomes. Spontaneous deamination of methylcytosine to thymine makes methylated cytosines unusually susceptible to mutation and consequent depletion. The loci where CG dinucleotides r...

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Detalles Bibliográficos
Autores principales: Glass, Jacob L., Thompson, Reid F., Khulan, Batbayar, Figueroa, Maria E., Olivier, Emmanuel N., Oakley, Erin J., Van Zant, Gary, Bouhassira, Eric E., Melnick, Ari, Golden, Aaron, Fazzari, Melissa J., Greally, John M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2007
Materias:
Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175314/
https://www.ncbi.nlm.nih.gov/pubmed/17932072
http://dx.doi.org/10.1093/nar/gkm489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175314/
https://www.ncbi.nlm.nih.gov/pubmed/17932072
http://dx.doi.org/10.1093/nar/gkm489

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