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Automethylation of G9a and its implication in wider substrate specificity and HP1 binding
Methylation of lysine residues on histones participates in transcriptional gene regulation. Lysine 9 methylation of histone H3 is a transcriptional repression signal, mediated by a family of SET domain containing AdoMet-dependent enzymes. G9a methyltransferase is a euchromatic histone H3 lysine 9 me...
Autores principales: | Chin, Hang Gyeong, Estève, Pierre-Olivier, Pradhan, Mihika, Benner, Jack, Patnaik, Debasis, Carey, Michael F., Pradhan, Sriharsa |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175347/ https://www.ncbi.nlm.nih.gov/pubmed/17962312 http://dx.doi.org/10.1093/nar/gkm726 |
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