Regulation of poly(ADP-ribose) polymerase-1 (PARP-1) gene expression through the post-translational modification of Sp1: a nuclear target protein of PARP-1

BACKGROUND: Poly(ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme that plays critical functions in many biological processes, including DNA repair and gene transcription. The main function of PARP-1 is to catalyze the transfer of ADP-ribose units from nicotinamide adenine dinucleotide (NAD(+))...

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Detalles Bibliográficos
Autores principales: Zaniolo, Karine, Desnoyers, Serge, Leclerc, Steeve, Guérin, Sylvain L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175517/
https://www.ncbi.nlm.nih.gov/pubmed/17961220
http://dx.doi.org/10.1186/1471-2199-8-96

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