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Beyond Parkinson Disease: Amyotrophic Lateral Sclerosis and the Axon Guidance Pathway

BACKGROUND: We recently described a genomic pathway approach to study complex diseases. We demonstrated that models constructed using single nucleotide polymorphisms (SNPs) within axon guidance pathway genes were highly predictive of Parkinson disease (PD) susceptibility, survival free of PD, and ag...

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Detalles Bibliográficos
Autores principales: Lesnick, Timothy G., Sorenson, Eric J., Ahlskog, J. Eric, Henley, John R., Shehadeh, Lina, Papapetropoulos, Spiridon, Maraganore, Demetrius M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175528/
https://www.ncbi.nlm.nih.gov/pubmed/18197259
http://dx.doi.org/10.1371/journal.pone.0001449