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Protection by the NDI1 Gene against Neurodegeneration in a Rotenone Rat Model of Parkinson's Disease

It is widely recognized that mitochondrial dysfunction, most notably defects in the NADH-quinone oxidoreductase (complex I), is closely related to the etiology of sporadic Parkinson's disease (PD). In fact, rotenone, a complex I inhibitor, has been used for establishing PD models both in vitro...

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Detalles Bibliográficos
Autores principales:	Marella, Mathieu, Seo, Byoung Boo, Nakamaru-Ogiso, Eiko, Greenamyre, J. Timothy, Matsuno-Yagi, Akemi, Yagi, Takao
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175531/ https://www.ncbi.nlm.nih.gov/pubmed/18197244 http://dx.doi.org/10.1371/journal.pone.0001433

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