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Differential var gene transcription in Plasmodium falciparum isolates from patients with cerebral malaria compared to hyperparasitaemia
The Plasmodium falciparum variant erythrocyte surface antigens known as PfEMP1, encoded by the var gene family, are thought to play a crucial role in malaria pathogenesis because they mediate adhesion to host cells and immuno-modulation. Var genes have been divided into three major groups (A, B and...
Autores principales: | Kyriacou, Helen M., Stone, Graham N., Challis, Richard J., Raza, Ahmed, Lyke, Kirsten E., Thera, Mahamadou A., Koné, Abdoulaye K., Doumbo, Ogobara K., Plowe, Christopher V., Rowe, J. Alexandra |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier/North-Holland Biomedical Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2176080/ https://www.ncbi.nlm.nih.gov/pubmed/16996149 http://dx.doi.org/10.1016/j.molbiopara.2006.08.005 |
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