Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool 'CubeX'

BACKGROUND: The frequency of a haplotype comprising one allele at each of two loci can be expressed as a cubic equation (the 'Hill equation'), the solution of which gives that frequency. Most haplotype and linkage disequilibrium analysis programs use iteration-based algorithms which substi...

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Detalles Bibliográficos
Autores principales: Gaunt, Tom R, Rodríguez, Santiago, Day, Ian NM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180187/
https://www.ncbi.nlm.nih.gov/pubmed/17980034
http://dx.doi.org/10.1186/1471-2105-8-428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180187/
https://www.ncbi.nlm.nih.gov/pubmed/17980034
http://dx.doi.org/10.1186/1471-2105-8-428

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