A Fast Signal–Induced Activation of Poly(Adp-Ribose) Polymerase: A Novel Downstream Target of Phospholipase C

We present the first evidence for a fast activation of the nuclear protein poly(ADP-ribose) polymerase (PARP) by signals evoked in the cell membrane, constituting a novel mode of signaling to the cell nucleus. PARP, an abundant, highly conserved, chromatin-bound protein found only in eukaryotes, exc...

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Detalles Bibliográficos
Autores principales: Homburg, S., Visochek, L., Moran, N., Dantzer, F., Priel, E., Asculai, E., Schwartz, D., Rotter, V., Dekel, N., Cohen-Armon, M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180227/
https://www.ncbi.nlm.nih.gov/pubmed/10908573

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