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ORAL IMMUNIZATION AGAINST PNEUMOCOCCUS TYPES II AND III AND THE NORMAL VARIATION IN RESISTANCE TO THESE TYPES AMONG RATS

1. Considerable variation in the resistance of different rats toward Type II pneumococcus has been demonstrated. In general, older rats survive much greater doses than young ones, illustrating the acquisition of a natural partial immunity. The same is true for Type III but the immunity appears somew...

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Detalles Bibliográficos
Autor principal: Ross, Victor
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1931
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180298/
https://www.ncbi.nlm.nih.gov/pubmed/19869966
Descripción
Sumario:1. Considerable variation in the resistance of different rats toward Type II pneumococcus has been demonstrated. In general, older rats survive much greater doses than young ones, illustrating the acquisition of a natural partial immunity. The same is true for Type III but the immunity appears somewhat later in life and does not reach the same height. 2. An active immunity can be created against Types II and III in rats by feeding the dead organisms or the Berkefeld filtrate of the bile salt-dissolved cells. This immunity resembles that obtained against Type I in several respects.