STUDIES ON THE SPECIFIC CHARACTERISTICS OF SYPHILITIC BLOOD PROTEINS : I. SURFACE TENSION AND SOLUBILITY

These experiments show: 1. That the surface tension of normal blood serum is considerably lowered by standing undisturbed for a period of 1 hour (time-drop). 2. That the greatest time-drop recorded is with serum diluted approximately 10,000 times in fresh serum, and 50,000 times in heated serum. 3....

Descripción completa

Detalles Bibliográficos
Autor principal: Walton, S. T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1931
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180299/
https://www.ncbi.nlm.nih.gov/pubmed/19869965
_version_ 1782145519105081344
author Walton, S. T.
author_facet Walton, S. T.
author_sort Walton, S. T.
collection PubMed
description These experiments show: 1. That the surface tension of normal blood serum is considerably lowered by standing undisturbed for a period of 1 hour (time-drop). 2. That the greatest time-drop recorded is with serum diluted approximately 10,000 times in fresh serum, and 50,000 times in heated serum. 3. That immune serum is not affected in the same manner by heat as is normal serum. Syphilitic serum and anti-sheep cell rabbit serum behave similarly in this respect. 4. That serum albumin is much more readily soluble in alkaline buffer solutions than globulin is, and that globulin from normal serum ionizes more than that from syphilitic serum. Further investigations are being made in an effort to determine why the proteins aggregate or dissociate under the influence of the factors under consideration.
format Text
id pubmed-2180299
institution National Center for Biotechnology Information
language English
publishDate 1931
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21802992008-04-18 STUDIES ON THE SPECIFIC CHARACTERISTICS OF SYPHILITIC BLOOD PROTEINS : I. SURFACE TENSION AND SOLUBILITY Walton, S. T. J Exp Med Article These experiments show: 1. That the surface tension of normal blood serum is considerably lowered by standing undisturbed for a period of 1 hour (time-drop). 2. That the greatest time-drop recorded is with serum diluted approximately 10,000 times in fresh serum, and 50,000 times in heated serum. 3. That immune serum is not affected in the same manner by heat as is normal serum. Syphilitic serum and anti-sheep cell rabbit serum behave similarly in this respect. 4. That serum albumin is much more readily soluble in alkaline buffer solutions than globulin is, and that globulin from normal serum ionizes more than that from syphilitic serum. Further investigations are being made in an effort to determine why the proteins aggregate or dissociate under the influence of the factors under consideration. The Rockefeller University Press 1931-11-30 /pmc/articles/PMC2180299/ /pubmed/19869965 Text en Copyright © Copyright, 1931, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Walton, S. T.
STUDIES ON THE SPECIFIC CHARACTERISTICS OF SYPHILITIC BLOOD PROTEINS : I. SURFACE TENSION AND SOLUBILITY
title STUDIES ON THE SPECIFIC CHARACTERISTICS OF SYPHILITIC BLOOD PROTEINS : I. SURFACE TENSION AND SOLUBILITY
title_full STUDIES ON THE SPECIFIC CHARACTERISTICS OF SYPHILITIC BLOOD PROTEINS : I. SURFACE TENSION AND SOLUBILITY
title_fullStr STUDIES ON THE SPECIFIC CHARACTERISTICS OF SYPHILITIC BLOOD PROTEINS : I. SURFACE TENSION AND SOLUBILITY
title_full_unstemmed STUDIES ON THE SPECIFIC CHARACTERISTICS OF SYPHILITIC BLOOD PROTEINS : I. SURFACE TENSION AND SOLUBILITY
title_short STUDIES ON THE SPECIFIC CHARACTERISTICS OF SYPHILITIC BLOOD PROTEINS : I. SURFACE TENSION AND SOLUBILITY
title_sort studies on the specific characteristics of syphilitic blood proteins : i. surface tension and solubility
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180299/
https://www.ncbi.nlm.nih.gov/pubmed/19869965
work_keys_str_mv AT waltonst studiesonthespecificcharacteristicsofsyphiliticbloodproteinsisurfacetensionandsolubility

Ejemplares similares