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ACTION OF METHYLENE BLUE ON BODY TEMPERATURE AND METABOLISM

1. Methylene blue injected intravenously in white rats is hyperthermizing or hypothermizing according to the environmental temperature. 2. It causes an increase in metabolism at 28°C. or above. At lower temperature it does not affect, or rather depresses, metabolism. 3. It does not seem likely that...

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Detalles Bibliográficos
Autor principal: Gregoire, P. E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1931
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180301/
https://www.ncbi.nlm.nih.gov/pubmed/19869963
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author Gregoire, P. E.
author_facet Gregoire, P. E.
author_sort Gregoire, P. E.
collection PubMed
description 1. Methylene blue injected intravenously in white rats is hyperthermizing or hypothermizing according to the environmental temperature. 2. It causes an increase in metabolism at 28°C. or above. At lower temperature it does not affect, or rather depresses, metabolism. 3. It does not seem likely that its hypermetabolic action is due to catalysis of cell oxidations. 4. In animals exposed to an atmosphere with a high partial pressure of oxygen, methylene blue causes pulmonary edema, much more rapidly than does oxygen alone.
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spelling pubmed-21803012008-04-18 ACTION OF METHYLENE BLUE ON BODY TEMPERATURE AND METABOLISM Gregoire, P. E. J Exp Med Article 1. Methylene blue injected intravenously in white rats is hyperthermizing or hypothermizing according to the environmental temperature. 2. It causes an increase in metabolism at 28°C. or above. At lower temperature it does not affect, or rather depresses, metabolism. 3. It does not seem likely that its hypermetabolic action is due to catalysis of cell oxidations. 4. In animals exposed to an atmosphere with a high partial pressure of oxygen, methylene blue causes pulmonary edema, much more rapidly than does oxygen alone. The Rockefeller University Press 1931-11-30 /pmc/articles/PMC2180301/ /pubmed/19869963 Text en Copyright © Copyright, 1931, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Gregoire, P. E.
ACTION OF METHYLENE BLUE ON BODY TEMPERATURE AND METABOLISM
title ACTION OF METHYLENE BLUE ON BODY TEMPERATURE AND METABOLISM
title_full ACTION OF METHYLENE BLUE ON BODY TEMPERATURE AND METABOLISM
title_fullStr ACTION OF METHYLENE BLUE ON BODY TEMPERATURE AND METABOLISM
title_full_unstemmed ACTION OF METHYLENE BLUE ON BODY TEMPERATURE AND METABOLISM
title_short ACTION OF METHYLENE BLUE ON BODY TEMPERATURE AND METABOLISM
title_sort action of methylene blue on body temperature and metabolism
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180301/
https://www.ncbi.nlm.nih.gov/pubmed/19869963
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