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ELECTRON MICROSCOPE STUDIES ON ULTRATHIN SECTIONS OF MUSCLE

Thin sections of striated muscle from frog (sartorius), rabbit (psoas), rat (heart), and fly (flight muscle), and of smooth muscle from clam (adductor) have been obtained using a new microtome. Electron micrographs of them are presented. The sections are sufficiently thin to achieve a resolution of...

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Detalles Bibliográficos
Autores principales: Hodge, Alan J., Huxley, Hugh E., Spiro, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1954
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180339/
https://www.ncbi.nlm.nih.gov/pubmed/13130794
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author Hodge, Alan J.
Huxley, Hugh E.
Spiro, David
author_facet Hodge, Alan J.
Huxley, Hugh E.
Spiro, David
author_sort Hodge, Alan J.
collection PubMed
description Thin sections of striated muscle from frog (sartorius), rabbit (psoas), rat (heart), and fly (flight muscle), and of smooth muscle from clam (adductor) have been obtained using a new microtome. Electron micrographs of them are presented. The sections are sufficiently thin to achieve a resolution of 30 to 40 A. In fly flight muscle, the myofibrils are distinct and well separated morphological units. In frog and rabbit muscle the myofibrils appear to be so closely packed under normal conditions that their identity as separate units is almost lost. In all types of striated muscle examined, it was found that the filaments are arranged within the myofibrils in a continuous and highly regular hexagonal array. The diameter of the filaments in embedded, sectioned muscle appears to be significantly less than that observed in dried shadowed material. The 400 A axial period, observed in frog and rabbit muscle, and in rat heart muscle, was found to extend across the interstitial material between the filaments. The significance of these findings is discussed.
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spelling pubmed-21803392008-04-17 ELECTRON MICROSCOPE STUDIES ON ULTRATHIN SECTIONS OF MUSCLE Hodge, Alan J. Huxley, Hugh E. Spiro, David J Exp Med Article Thin sections of striated muscle from frog (sartorius), rabbit (psoas), rat (heart), and fly (flight muscle), and of smooth muscle from clam (adductor) have been obtained using a new microtome. Electron micrographs of them are presented. The sections are sufficiently thin to achieve a resolution of 30 to 40 A. In fly flight muscle, the myofibrils are distinct and well separated morphological units. In frog and rabbit muscle the myofibrils appear to be so closely packed under normal conditions that their identity as separate units is almost lost. In all types of striated muscle examined, it was found that the filaments are arranged within the myofibrils in a continuous and highly regular hexagonal array. The diameter of the filaments in embedded, sectioned muscle appears to be significantly less than that observed in dried shadowed material. The 400 A axial period, observed in frog and rabbit muscle, and in rat heart muscle, was found to extend across the interstitial material between the filaments. The significance of these findings is discussed. The Rockefeller University Press 1954-01-31 /pmc/articles/PMC2180339/ /pubmed/13130794 Text en Copyright © Copyright, 1954, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Hodge, Alan J.
Huxley, Hugh E.
Spiro, David
ELECTRON MICROSCOPE STUDIES ON ULTRATHIN SECTIONS OF MUSCLE
title ELECTRON MICROSCOPE STUDIES ON ULTRATHIN SECTIONS OF MUSCLE
title_full ELECTRON MICROSCOPE STUDIES ON ULTRATHIN SECTIONS OF MUSCLE
title_fullStr ELECTRON MICROSCOPE STUDIES ON ULTRATHIN SECTIONS OF MUSCLE
title_full_unstemmed ELECTRON MICROSCOPE STUDIES ON ULTRATHIN SECTIONS OF MUSCLE
title_short ELECTRON MICROSCOPE STUDIES ON ULTRATHIN SECTIONS OF MUSCLE
title_sort electron microscope studies on ultrathin sections of muscle
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180339/
https://www.ncbi.nlm.nih.gov/pubmed/13130794
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