THE VACUOLATING VIRUS OF MONKEYS : II. VIRUS MORPHOLOGY AND INTRANUCLEAR DISTRIBUTION WITH SOME HISTOCHEMICAL OBSERVATIONS

Cells infected with the vacuolating virus, SV(40), respond by swelling to several times their normal volume. Within enlarged nuclei, virus-containing inclusions appear which are acidophilic and Feulgen-positive. The formation of nuclear inclusions is followed by the appearance of cytoplasmic vacuole...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaylord, W. H., Hsiung, G.-D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1961
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180416/
https://www.ncbi.nlm.nih.gov/pubmed/13897378
Descripción
Sumario:Cells infected with the vacuolating virus, SV(40), respond by swelling to several times their normal volume. Within enlarged nuclei, virus-containing inclusions appear which are acidophilic and Feulgen-positive. The formation of nuclear inclusions is followed by the appearance of cytoplasmic vacuoles and then shrinkage of the cell. Inclusions were found to exhibit unique double staining when a light-green counterstain was used in the Feulgen reaction. The virus is of low electron density, round, and 300 A in diameter. It occurs in large numbers, singly and in short chains, and it appears to multiply at the expense of chromatin.

Ejemplares similares