THE VACUOLATING VIRUS OF MONKEYS : II. VIRUS MORPHOLOGY AND INTRANUCLEAR DISTRIBUTION WITH SOME HISTOCHEMICAL OBSERVATIONS

Cells infected with the vacuolating virus, SV(40), respond by swelling to several times their normal volume. Within enlarged nuclei, virus-containing inclusions appear which are acidophilic and Feulgen-positive. The formation of nuclear inclusions is followed by the appearance of cytoplasmic vacuole...

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Detalles Bibliográficos
Autores principales: Gaylord, W. H., Hsiung, G.-D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1961
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180416/
https://www.ncbi.nlm.nih.gov/pubmed/13897378
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author Gaylord, W. H.
Hsiung, G.-D.
author_facet Gaylord, W. H.
Hsiung, G.-D.
author_sort Gaylord, W. H.
collection PubMed
description Cells infected with the vacuolating virus, SV(40), respond by swelling to several times their normal volume. Within enlarged nuclei, virus-containing inclusions appear which are acidophilic and Feulgen-positive. The formation of nuclear inclusions is followed by the appearance of cytoplasmic vacuoles and then shrinkage of the cell. Inclusions were found to exhibit unique double staining when a light-green counterstain was used in the Feulgen reaction. The virus is of low electron density, round, and 300 A in diameter. It occurs in large numbers, singly and in short chains, and it appears to multiply at the expense of chromatin.
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spelling pubmed-21804162008-04-17 THE VACUOLATING VIRUS OF MONKEYS : II. VIRUS MORPHOLOGY AND INTRANUCLEAR DISTRIBUTION WITH SOME HISTOCHEMICAL OBSERVATIONS Gaylord, W. H. Hsiung, G.-D. J Exp Med Article Cells infected with the vacuolating virus, SV(40), respond by swelling to several times their normal volume. Within enlarged nuclei, virus-containing inclusions appear which are acidophilic and Feulgen-positive. The formation of nuclear inclusions is followed by the appearance of cytoplasmic vacuoles and then shrinkage of the cell. Inclusions were found to exhibit unique double staining when a light-green counterstain was used in the Feulgen reaction. The virus is of low electron density, round, and 300 A in diameter. It occurs in large numbers, singly and in short chains, and it appears to multiply at the expense of chromatin. The Rockefeller University Press 1961-11-30 /pmc/articles/PMC2180416/ /pubmed/13897378 Text en Copyright © Copyright, 1961, by The Rockefeller Institute This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Gaylord, W. H.
Hsiung, G.-D.
THE VACUOLATING VIRUS OF MONKEYS : II. VIRUS MORPHOLOGY AND INTRANUCLEAR DISTRIBUTION WITH SOME HISTOCHEMICAL OBSERVATIONS
title THE VACUOLATING VIRUS OF MONKEYS : II. VIRUS MORPHOLOGY AND INTRANUCLEAR DISTRIBUTION WITH SOME HISTOCHEMICAL OBSERVATIONS
title_full THE VACUOLATING VIRUS OF MONKEYS : II. VIRUS MORPHOLOGY AND INTRANUCLEAR DISTRIBUTION WITH SOME HISTOCHEMICAL OBSERVATIONS
title_fullStr THE VACUOLATING VIRUS OF MONKEYS : II. VIRUS MORPHOLOGY AND INTRANUCLEAR DISTRIBUTION WITH SOME HISTOCHEMICAL OBSERVATIONS
title_full_unstemmed THE VACUOLATING VIRUS OF MONKEYS : II. VIRUS MORPHOLOGY AND INTRANUCLEAR DISTRIBUTION WITH SOME HISTOCHEMICAL OBSERVATIONS
title_short THE VACUOLATING VIRUS OF MONKEYS : II. VIRUS MORPHOLOGY AND INTRANUCLEAR DISTRIBUTION WITH SOME HISTOCHEMICAL OBSERVATIONS
title_sort vacuolating virus of monkeys : ii. virus morphology and intranuclear distribution with some histochemical observations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180416/
https://www.ncbi.nlm.nih.gov/pubmed/13897378
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