HISTOCOMPATIBILITY TYPE AND IMMUNE RESPONSIVENESS IN RANDOM BRED HARTLEY STRAIN GUINEA PIGS

Outbred Hartley strain guinea pigs capable of responding immunologically to 2,4-dinitrophenylated poly-L-lysine were shown to display a histocompatibility specificity in common with inbred strain 2 guinea pigs. This histocompatibility specificity was not detected in guinea pigs unable to respond imm...

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Detalles Bibliográficos
Autores principales: Martin, William John, Ellman, Leonard, Green, Ira, Benacerraf, Baruj
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1970
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180499/
https://www.ncbi.nlm.nih.gov/pubmed/5511572
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author Martin, William John
Ellman, Leonard
Green, Ira
Benacerraf, Baruj
author_facet Martin, William John
Ellman, Leonard
Green, Ira
Benacerraf, Baruj
author_sort Martin, William John
collection PubMed
description Outbred Hartley strain guinea pigs capable of responding immunologically to 2,4-dinitrophenylated poly-L-lysine were shown to display a histocompatibility specificity in common with inbred strain 2 guinea pigs. This histocompatibility specificity was not detected in guinea pigs unable to respond immunologically to DNP-PLL. The result suggests that the poly-L-lysine specific immune response gene is very closely linked or even identical with a gene determining a major histocompatibility antigen in guinea pigs.
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spelling pubmed-21804992008-04-17 HISTOCOMPATIBILITY TYPE AND IMMUNE RESPONSIVENESS IN RANDOM BRED HARTLEY STRAIN GUINEA PIGS Martin, William John Ellman, Leonard Green, Ira Benacerraf, Baruj J Exp Med Article Outbred Hartley strain guinea pigs capable of responding immunologically to 2,4-dinitrophenylated poly-L-lysine were shown to display a histocompatibility specificity in common with inbred strain 2 guinea pigs. This histocompatibility specificity was not detected in guinea pigs unable to respond immunologically to DNP-PLL. The result suggests that the poly-L-lysine specific immune response gene is very closely linked or even identical with a gene determining a major histocompatibility antigen in guinea pigs. The Rockefeller University Press 1970-11-30 /pmc/articles/PMC2180499/ /pubmed/5511572 Text en Copyright © 1970 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Martin, William John
Ellman, Leonard
Green, Ira
Benacerraf, Baruj
HISTOCOMPATIBILITY TYPE AND IMMUNE RESPONSIVENESS IN RANDOM BRED HARTLEY STRAIN GUINEA PIGS
title HISTOCOMPATIBILITY TYPE AND IMMUNE RESPONSIVENESS IN RANDOM BRED HARTLEY STRAIN GUINEA PIGS
title_full HISTOCOMPATIBILITY TYPE AND IMMUNE RESPONSIVENESS IN RANDOM BRED HARTLEY STRAIN GUINEA PIGS
title_fullStr HISTOCOMPATIBILITY TYPE AND IMMUNE RESPONSIVENESS IN RANDOM BRED HARTLEY STRAIN GUINEA PIGS
title_full_unstemmed HISTOCOMPATIBILITY TYPE AND IMMUNE RESPONSIVENESS IN RANDOM BRED HARTLEY STRAIN GUINEA PIGS
title_short HISTOCOMPATIBILITY TYPE AND IMMUNE RESPONSIVENESS IN RANDOM BRED HARTLEY STRAIN GUINEA PIGS
title_sort histocompatibility type and immune responsiveness in random bred hartley strain guinea pigs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180499/
https://www.ncbi.nlm.nih.gov/pubmed/5511572
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AT greenira histocompatibilitytypeandimmuneresponsivenessinrandombredhartleystrainguineapigs
AT benacerrafbaruj histocompatibilitytypeandimmuneresponsivenessinrandombredhartleystrainguineapigs

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