THE SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : VI. ASSEMBLY OF IGM PROTEINS

The study of the synthesis, assembly, and secretion of IgM by seven murine myeloma tumors has revealed that free mu chain can be detected intracellularly after release from the ribosome. It combines with light chains to form µL. The major intracellular protein in six of the seven tumors was the 8S s...

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Detalles Bibliográficos
Autores principales: Buxbaum, J., Scharff, M. D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1973
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180535/
https://www.ncbi.nlm.nih.gov/pubmed/4717123
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author Buxbaum, J.
Scharff, M. D.
author_facet Buxbaum, J.
Scharff, M. D.
author_sort Buxbaum, J.
collection PubMed
description The study of the synthesis, assembly, and secretion of IgM by seven murine myeloma tumors has revealed that free mu chain can be detected intracellularly after release from the ribosome. It combines with light chains to form µL. The major intracellular protein in six of the seven tumors was the 8S subunit. One tumor contained considerable amounts of 19S material intracellularly. Those tumors that did not contain 19S IgM intracellulariy appeared to assemble the subunits outside the cell.
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spelling pubmed-21805352008-04-17 THE SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : VI. ASSEMBLY OF IGM PROTEINS Buxbaum, J. Scharff, M. D. J Exp Med Article The study of the synthesis, assembly, and secretion of IgM by seven murine myeloma tumors has revealed that free mu chain can be detected intracellularly after release from the ribosome. It combines with light chains to form µL. The major intracellular protein in six of the seven tumors was the 8S subunit. One tumor contained considerable amounts of 19S material intracellularly. Those tumors that did not contain 19S IgM intracellulariy appeared to assemble the subunits outside the cell. The Rockefeller University Press 1973-07-01 /pmc/articles/PMC2180535/ /pubmed/4717123 Text en Copyright © 1973 by The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Buxbaum, J.
Scharff, M. D.
THE SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : VI. ASSEMBLY OF IGM PROTEINS
title THE SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : VI. ASSEMBLY OF IGM PROTEINS
title_full THE SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : VI. ASSEMBLY OF IGM PROTEINS
title_fullStr THE SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : VI. ASSEMBLY OF IGM PROTEINS
title_full_unstemmed THE SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : VI. ASSEMBLY OF IGM PROTEINS
title_short THE SYNTHESIS, ASSEMBLY, AND SECRETION OF GAMMA GLOBULIN BY MOUSE MYELOMA CELLS : VI. ASSEMBLY OF IGM PROTEINS
title_sort synthesis, assembly, and secretion of gamma globulin by mouse myeloma cells : vi. assembly of igm proteins
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180535/
https://www.ncbi.nlm.nih.gov/pubmed/4717123
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