Immune mechanisms in leukemia role of the Ia antigens

We have shown that the selective removal of cells possessing Ia determinants coded by the I-A, I-B, and I-J regions of the H-2 gene complex completely abrogates the protective capacity of nylon-wool- purified T lymphocytes against leukemic challenge. This suggests that the Ia antigen bearing T cells...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1977
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180632/
https://www.ncbi.nlm.nih.gov/pubmed/67166
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description We have shown that the selective removal of cells possessing Ia determinants coded by the I-A, I-B, and I-J regions of the H-2 gene complex completely abrogates the protective capacity of nylon-wool- purified T lymphocytes against leukemic challenge. This suggests that the Ia antigen bearing T cells play an important role in tumor immunity.
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spelling pubmed-21806322008-04-17 Immune mechanisms in leukemia role of the Ia antigens J Exp Med Articles We have shown that the selective removal of cells possessing Ia determinants coded by the I-A, I-B, and I-J regions of the H-2 gene complex completely abrogates the protective capacity of nylon-wool- purified T lymphocytes against leukemic challenge. This suggests that the Ia antigen bearing T cells play an important role in tumor immunity. The Rockefeller University Press 1977-04-01 /pmc/articles/PMC2180632/ /pubmed/67166 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Immune mechanisms in leukemia role of the Ia antigens
title Immune mechanisms in leukemia role of the Ia antigens
title_full Immune mechanisms in leukemia role of the Ia antigens
title_fullStr Immune mechanisms in leukemia role of the Ia antigens
title_full_unstemmed Immune mechanisms in leukemia role of the Ia antigens
title_short Immune mechanisms in leukemia role of the Ia antigens
title_sort immune mechanisms in leukemia role of the ia antigens
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180632/
https://www.ncbi.nlm.nih.gov/pubmed/67166

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