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Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses
Antisera to the type-specific internal influenza virus matrix (M) protein of a type A influenza virus were produced in goats. In the presence of complement, anti-M serum was cytotoxic for target cells which were infected with a variety of serologically distinct type A influenza viruses, but did not...
Formato: | Texto |
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Lenguaje: | English |
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The Rockefeller University Press
1977
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180789/ https://www.ncbi.nlm.nih.gov/pubmed/70496 |
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collection | PubMed |
description | Antisera to the type-specific internal influenza virus matrix (M) protein of a type A influenza virus were produced in goats. In the presence of complement, anti-M serum was cytotoxic for target cells which were infected with a variety of serologically distinct type A influenza viruses, but did not react with type B influenza virus- infected cells. Absorption experiments indicated that anti-M serum detected a common antigen(s) on the surface of type A-infected cells. This serological cross-reactivity parallels the cross-reactivity observed for the cytotoxic T-cell response to type A viruses. |
format | Text |
id | pubmed-2180789 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1977 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21807892008-04-17 Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses J Exp Med Articles Antisera to the type-specific internal influenza virus matrix (M) protein of a type A influenza virus were produced in goats. In the presence of complement, anti-M serum was cytotoxic for target cells which were infected with a variety of serologically distinct type A influenza viruses, but did not react with type B influenza virus- infected cells. Absorption experiments indicated that anti-M serum detected a common antigen(s) on the surface of type A-infected cells. This serological cross-reactivity parallels the cross-reactivity observed for the cytotoxic T-cell response to type A viruses. The Rockefeller University Press 1977-09-01 /pmc/articles/PMC2180789/ /pubmed/70496 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses |
title | Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses |
title_full | Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses |
title_fullStr | Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses |
title_full_unstemmed | Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses |
title_short | Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses |
title_sort | antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type a influenza viruses |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180789/ https://www.ncbi.nlm.nih.gov/pubmed/70496 |