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Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses

Antisera to the type-specific internal influenza virus matrix (M) protein of a type A influenza virus were produced in goats. In the presence of complement, anti-M serum was cytotoxic for target cells which were infected with a variety of serologically distinct type A influenza viruses, but did not...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1977
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180789/
https://www.ncbi.nlm.nih.gov/pubmed/70496
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description Antisera to the type-specific internal influenza virus matrix (M) protein of a type A influenza virus were produced in goats. In the presence of complement, anti-M serum was cytotoxic for target cells which were infected with a variety of serologically distinct type A influenza viruses, but did not react with type B influenza virus- infected cells. Absorption experiments indicated that anti-M serum detected a common antigen(s) on the surface of type A-infected cells. This serological cross-reactivity parallels the cross-reactivity observed for the cytotoxic T-cell response to type A viruses.
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spelling pubmed-21807892008-04-17 Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses J Exp Med Articles Antisera to the type-specific internal influenza virus matrix (M) protein of a type A influenza virus were produced in goats. In the presence of complement, anti-M serum was cytotoxic for target cells which were infected with a variety of serologically distinct type A influenza viruses, but did not react with type B influenza virus- infected cells. Absorption experiments indicated that anti-M serum detected a common antigen(s) on the surface of type A-infected cells. This serological cross-reactivity parallels the cross-reactivity observed for the cytotoxic T-cell response to type A viruses. The Rockefeller University Press 1977-09-01 /pmc/articles/PMC2180789/ /pubmed/70496 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses
title Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses
title_full Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses
title_fullStr Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses
title_full_unstemmed Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses
title_short Antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type A influenza viruses
title_sort antibody to influenza virus matrix protein detects a common antigen on the surface of cells infected with type a influenza viruses
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180789/
https://www.ncbi.nlm.nih.gov/pubmed/70496