Release from maternally-induced allotypic suppression in rabbit by Nocardia water-soluble mitogen

The in vitro synthesis of allotypes of b4/b5 offspring obtained from b4/b4 mothers immunized against paternal allotype b5/b5 was studied in comparison to similar offspring that had escaped from suppression and normal heterozygous b4/b5 rabbits. Nocardia water-soluble mitogen-a rabbit B-cell mitogen...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1977
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180791/
https://www.ncbi.nlm.nih.gov/pubmed/894191
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collection PubMed
description The in vitro synthesis of allotypes of b4/b5 offspring obtained from b4/b4 mothers immunized against paternal allotype b5/b5 was studied in comparison to similar offspring that had escaped from suppression and normal heterozygous b4/b5 rabbits. Nocardia water-soluble mitogen-a rabbit B-cell mitogen which is known to induce the differentiation of small lymphocytes into plasma cells and polyclonal activation of Ig, was able to break in vitro the allotypic suppression induced in vivo.
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spelling pubmed-21807912008-04-17 Release from maternally-induced allotypic suppression in rabbit by Nocardia water-soluble mitogen J Exp Med Articles The in vitro synthesis of allotypes of b4/b5 offspring obtained from b4/b4 mothers immunized against paternal allotype b5/b5 was studied in comparison to similar offspring that had escaped from suppression and normal heterozygous b4/b5 rabbits. Nocardia water-soluble mitogen-a rabbit B-cell mitogen which is known to induce the differentiation of small lymphocytes into plasma cells and polyclonal activation of Ig, was able to break in vitro the allotypic suppression induced in vivo. The Rockefeller University Press 1977-09-01 /pmc/articles/PMC2180791/ /pubmed/894191 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Release from maternally-induced allotypic suppression in rabbit by Nocardia water-soluble mitogen
title Release from maternally-induced allotypic suppression in rabbit by Nocardia water-soluble mitogen
title_full Release from maternally-induced allotypic suppression in rabbit by Nocardia water-soluble mitogen
title_fullStr Release from maternally-induced allotypic suppression in rabbit by Nocardia water-soluble mitogen
title_full_unstemmed Release from maternally-induced allotypic suppression in rabbit by Nocardia water-soluble mitogen
title_short Release from maternally-induced allotypic suppression in rabbit by Nocardia water-soluble mitogen
title_sort release from maternally-induced allotypic suppression in rabbit by nocardia water-soluble mitogen
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180791/
https://www.ncbi.nlm.nih.gov/pubmed/894191

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