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Ontogeny of cell-mediated immunity. I. Early development of alloantigen- specific cytotoxic T-cell precursors in postnatal mice

Cytotoxic T-cell precursors have been shown to occur in spleens of 2-3- day-old mice. By 12 days after birth, the cytotoxic T-cell response of spleen cells to alloantigens has reached 23-32% of adult levels. Addition of extra T-helper cells did not permit cytotoxic T-cell development in spleen cells...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1977
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180800/
https://www.ncbi.nlm.nih.gov/pubmed/302309