Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers

Mice with the CBA/N defect are unresponsive to the hapten phosphorylcholine (PC) even when presented on a variety of immunogenic carriers. Since these mice have the variable region gene for PC, their inability to respond may reflect deletion or suppression of the line of B lymphocytes which is respo...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1977
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180827/
https://www.ncbi.nlm.nih.gov/pubmed/302313
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collection PubMed
description Mice with the CBA/N defect are unresponsive to the hapten phosphorylcholine (PC) even when presented on a variety of immunogenic carriers. Since these mice have the variable region gene for PC, their inability to respond may reflect deletion or suppression of the line of B lymphocytes which is responsible for the anti-PC response.
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spelling pubmed-21808272008-04-17 Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers J Exp Med Articles Mice with the CBA/N defect are unresponsive to the hapten phosphorylcholine (PC) even when presented on a variety of immunogenic carriers. Since these mice have the variable region gene for PC, their inability to respond may reflect deletion or suppression of the line of B lymphocytes which is responsible for the anti-PC response. The Rockefeller University Press 1977-10-01 /pmc/articles/PMC2180827/ /pubmed/302313 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers
title Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers
title_full Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers
title_fullStr Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers
title_full_unstemmed Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers
title_short Inability of mice with a defect in B-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers
title_sort inability of mice with a defect in b-lymphocyte maturation to respond to phosphorycholine on immunogenic carriers
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180827/
https://www.ncbi.nlm.nih.gov/pubmed/302313

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