Enrichment of specific suppressor T cells and characterization of their surface markers

A simple method is described which allows antigen-specific suppressor T cells to be enriched by greater than 100-fold. The enriched cells have the following characteristic markers: Ig-, Thy-1+, Ly-1-, Ly-2,3+, and I-J+. More than 30% of this population could be killed directly by an antiserum specif...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1977
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180969/
https://www.ncbi.nlm.nih.gov/pubmed/303682
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collection PubMed
description A simple method is described which allows antigen-specific suppressor T cells to be enriched by greater than 100-fold. The enriched cells have the following characteristic markers: Ig-, Thy-1+, Ly-1-, Ly-2,3+, and I-J+. More than 30% of this population could be killed directly by an antiserum specific for the I-J subregion gene product in the presence of complement.
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spelling pubmed-21809692008-04-17 Enrichment of specific suppressor T cells and characterization of their surface markers J Exp Med Articles A simple method is described which allows antigen-specific suppressor T cells to be enriched by greater than 100-fold. The enriched cells have the following characteristic markers: Ig-, Thy-1+, Ly-1-, Ly-2,3+, and I-J+. More than 30% of this population could be killed directly by an antiserum specific for the I-J subregion gene product in the presence of complement. The Rockefeller University Press 1977-11-01 /pmc/articles/PMC2180969/ /pubmed/303682 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Enrichment of specific suppressor T cells and characterization of their surface markers
title Enrichment of specific suppressor T cells and characterization of their surface markers
title_full Enrichment of specific suppressor T cells and characterization of their surface markers
title_fullStr Enrichment of specific suppressor T cells and characterization of their surface markers
title_full_unstemmed Enrichment of specific suppressor T cells and characterization of their surface markers
title_short Enrichment of specific suppressor T cells and characterization of their surface markers
title_sort enrichment of specific suppressor t cells and characterization of their surface markers
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180969/
https://www.ncbi.nlm.nih.gov/pubmed/303682

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