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Passive transfer of autoimmune disease with isologous IgG1 and IgG2 antibodies to the tubular basement membrane in strain XIII guinea pigs: loss of self-tolerance induced by autoantibodies
Initiation of an autoimmune tubulointerstitial disease was achieved in strain XIII guinea pigs by passive transfer of functionally pure IgG1 or IgG2 fractions of isologous anti-tubular basement membrane (TBM) serum. IgG2 appeared to be somewhat more effective than IgG1. The immunopathologic features...
| Formato: | Texto |
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| Lenguaje: | English |
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The Rockefeller University Press
1977
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2180980/ https://www.ncbi.nlm.nih.gov/pubmed/925602 |