Immunochemical evidence for three Ia loci in the I-region of the H-2 complex

Sequential immunoprecipitation analyses of Ia antigens were performed with 125I-labeled B10, B10.A(3R), and B10.A(5R) spleen cell lysates. The results suggest the presence of one I-region associated (Ia) locus (Ia-1) in the I-A subregion. In addition, they indicate that two Ia loci map between the I...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1977
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2181892/
https://www.ncbi.nlm.nih.gov/pubmed/72779
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collection PubMed
description Sequential immunoprecipitation analyses of Ia antigens were performed with 125I-labeled B10, B10.A(3R), and B10.A(5R) spleen cell lysates. The results suggest the presence of one I-region associated (Ia) locus (Ia-1) in the I-A subregion. In addition, they indicate that two Ia loci map between the I-J and S regions. One locus, Ia-5, maps in the I- E subregion. The second locus, most likely Ia-3, maps in either the I-E or I-C subregion. Taken together, the data demonstrate that at least three Ia loci in the I-region of the H-2 complex code for molecules detectable by immunoprecipitation.
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spelling pubmed-21818922008-04-17 Immunochemical evidence for three Ia loci in the I-region of the H-2 complex J Exp Med Articles Sequential immunoprecipitation analyses of Ia antigens were performed with 125I-labeled B10, B10.A(3R), and B10.A(5R) spleen cell lysates. The results suggest the presence of one I-region associated (Ia) locus (Ia-1) in the I-A subregion. In addition, they indicate that two Ia loci map between the I-J and S regions. One locus, Ia-5, maps in the I- E subregion. The second locus, most likely Ia-3, maps in either the I-E or I-C subregion. Taken together, the data demonstrate that at least three Ia loci in the I-region of the H-2 complex code for molecules detectable by immunoprecipitation. The Rockefeller University Press 1977-12-01 /pmc/articles/PMC2181892/ /pubmed/72779 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Immunochemical evidence for three Ia loci in the I-region of the H-2 complex
title Immunochemical evidence for three Ia loci in the I-region of the H-2 complex
title_full Immunochemical evidence for three Ia loci in the I-region of the H-2 complex
title_fullStr Immunochemical evidence for three Ia loci in the I-region of the H-2 complex
title_full_unstemmed Immunochemical evidence for three Ia loci in the I-region of the H-2 complex
title_short Immunochemical evidence for three Ia loci in the I-region of the H-2 complex
title_sort immunochemical evidence for three ia loci in the i-region of the h-2 complex
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2181892/
https://www.ncbi.nlm.nih.gov/pubmed/72779

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