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Cytotoxic T-cell responses to H-Y: correlation with the rejection of syngeneic male skin grafts

The ability of female mice to rapidly reject syngenic male skin grafts is largely determined by dominant genes in the IB region of the H-2b halotype, whereas the ability to produce anti-H-Y cytotoxic cells is determined by a dominant gene in the IA region the H-2b halotype, or by complementary genes...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1978
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2184192/
https://www.ncbi.nlm.nih.gov/pubmed/416166
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description The ability of female mice to rapidly reject syngenic male skin grafts is largely determined by dominant genes in the IB region of the H-2b halotype, whereas the ability to produce anti-H-Y cytotoxic cells is determined by a dominant gene in the IA region the H-2b halotype, or by complementary genes in the IC region of some other haplotypes. Thus, it seems that H-2-retricted anti-H-Y cytotoxic T cells are not responsible for the rejection of syngeneic male skin grafts.
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spelling pubmed-21841922008-04-17 Cytotoxic T-cell responses to H-Y: correlation with the rejection of syngeneic male skin grafts J Exp Med Articles The ability of female mice to rapidly reject syngenic male skin grafts is largely determined by dominant genes in the IB region of the H-2b halotype, whereas the ability to produce anti-H-Y cytotoxic cells is determined by a dominant gene in the IA region the H-2b halotype, or by complementary genes in the IC region of some other haplotypes. Thus, it seems that H-2-retricted anti-H-Y cytotoxic T cells are not responsible for the rejection of syngeneic male skin grafts. The Rockefeller University Press 1978-03-01 /pmc/articles/PMC2184192/ /pubmed/416166 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Cytotoxic T-cell responses to H-Y: correlation with the rejection of syngeneic male skin grafts
title Cytotoxic T-cell responses to H-Y: correlation with the rejection of syngeneic male skin grafts
title_full Cytotoxic T-cell responses to H-Y: correlation with the rejection of syngeneic male skin grafts
title_fullStr Cytotoxic T-cell responses to H-Y: correlation with the rejection of syngeneic male skin grafts
title_full_unstemmed Cytotoxic T-cell responses to H-Y: correlation with the rejection of syngeneic male skin grafts
title_short Cytotoxic T-cell responses to H-Y: correlation with the rejection of syngeneic male skin grafts
title_sort cytotoxic t-cell responses to h-y: correlation with the rejection of syngeneic male skin grafts
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2184192/
https://www.ncbi.nlm.nih.gov/pubmed/416166