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A macrophage tumor cell line and plasminogen activator. A potential model system for macrophage regulation of enzyme production
The macrophage cell line, RAW264.10, synthesizes and secretes plasminogen activator. Production of this enzyme is inhibited by low concentrations of glucocorticoids and increased by phorbol myristate acetate. It is proposed that this line could be a suitable model for the regulation of enzyme synthe...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1978
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185004/ https://www.ncbi.nlm.nih.gov/pubmed/702056 |
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collection | PubMed |
description | The macrophage cell line, RAW264.10, synthesizes and secretes plasminogen activator. Production of this enzyme is inhibited by low concentrations of glucocorticoids and increased by phorbol myristate acetate. It is proposed that this line could be a suitable model for the regulation of enzyme synthesis by mouse peritoneal macrophages. |
format | Text |
id | pubmed-2185004 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1978 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21850042008-04-17 A macrophage tumor cell line and plasminogen activator. A potential model system for macrophage regulation of enzyme production J Exp Med Articles The macrophage cell line, RAW264.10, synthesizes and secretes plasminogen activator. Production of this enzyme is inhibited by low concentrations of glucocorticoids and increased by phorbol myristate acetate. It is proposed that this line could be a suitable model for the regulation of enzyme synthesis by mouse peritoneal macrophages. The Rockefeller University Press 1978-09-01 /pmc/articles/PMC2185004/ /pubmed/702056 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Articles A macrophage tumor cell line and plasminogen activator. A potential model system for macrophage regulation of enzyme production |
title | A macrophage tumor cell line and plasminogen activator. A potential model system for macrophage regulation of enzyme production |
title_full | A macrophage tumor cell line and plasminogen activator. A potential model system for macrophage regulation of enzyme production |
title_fullStr | A macrophage tumor cell line and plasminogen activator. A potential model system for macrophage regulation of enzyme production |
title_full_unstemmed | A macrophage tumor cell line and plasminogen activator. A potential model system for macrophage regulation of enzyme production |
title_short | A macrophage tumor cell line and plasminogen activator. A potential model system for macrophage regulation of enzyme production |
title_sort | macrophage tumor cell line and plasminogen activator. a potential model system for macrophage regulation of enzyme production |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185004/ https://www.ncbi.nlm.nih.gov/pubmed/702056 |