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Tissue Transglutaminase Does Not Contribute to the Formation of Mutant Huntingtin Aggregates

The cause of Huntington's disease (HD) is a pathological expansion of the polyglutamine domain within the NH(2)-terminal region of huntingtin. Neuronal intranuclear inclusions and cytoplasmic aggregates composed of the mutant huntingtin within certain neuronal populations are a characteristic h...

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Detalles Bibliográficos
Autores principales:	Chun, Wanjoo, Lesort, Mathieu, Tucholski, Janusz, Ross, Christopher A., Johnson, Gail V.W.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2001
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185516/ https://www.ncbi.nlm.nih.gov/pubmed/11285271

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