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Glutamate Slows Axonal Transport of Neurofilaments in Transfected Neurons
Neurofilaments are transported through axons by slow axonal transport. Abnormal accumulations of neurofilaments are seen in several neurodegenerative diseases, and this suggests that neurofilament transport is defective. Excitotoxic mechanisms involving glutamate are believed to be part of the patho...
Autores principales: | Ackerley, Steven, Grierson, Andrew J., Brownlees, Janet, Thornhill, Paul, Anderton, Brian H., Leigh, P. Nigel, Shaw, Christopher E., Miller, Christopher C.J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185569/ https://www.ncbi.nlm.nih.gov/pubmed/10893265 |
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