Sphingomyelin Hydrolysis to Ceramide during the Execution Phase of Apoptosis Results from Phospholipid Scrambling and Alters Cell-Surface Morphology

Apoptosis is generally accompanied by a late phase of ceramide (Cer) production, the significance of which is unknown. This study describes a previously unrecognized link between Cer accumulation and phosphatidylserine (PS) exposure at the cell surface, a characteristic of the execution phase of apo...

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Detalles Bibliográficos
Autores principales: Tepper, Annemiek D., Ruurs, Paula, Wiedmer, Therese, Sims, Peter J., Borst, Jannie, van Blitterswijk, Wim J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185573/
https://www.ncbi.nlm.nih.gov/pubmed/10893264

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