Evidence for Segregation of Sphingomyelin and Cholesterol during Formation of Copi-Coated Vesicles

In higher eukaryotes, phospholipid and cholesterol synthesis occurs mainly in the endoplasmic reticulum, whereas sphingomyelin and higher glycosphingolipids are synthesized in the Golgi apparatus. Lipids like cholesterol and sphingomyelin are gradually enriched along the secretory pathway, with thei...

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Detalles Bibliográficos
Autores principales: Brügger, Britta, Sandhoff, Roger, Wegehingel, Sabine, Gorgas, Karin, Malsam, Jörg, Helms, J. Bernd, Lehmann, Wolf-Dieter, Nickel, Walter, Wieland, Felix T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185577/
https://www.ncbi.nlm.nih.gov/pubmed/11062253

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