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The Dendritic Cell Receptor for Endocytosis, Dec-205, Can Recycle and Enhance Antigen Presentation via Major Histocompatibility Complex Class II–Positive Lysosomal Compartments

Many receptors for endocytosis recycle into and out of cells through early endosomes. We now find in dendritic cells that the DEC-205 multilectin receptor targets late endosomes or lysosomes rich in major histocompatibility complex class II (MHC II) products, whereas the homologous macrophage mannos...

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Detalles Bibliográficos
Autores principales: Mahnke, Karsten, Guo, Ming, Lee, Sena, Sepulveda, Homero, Swain, Suzy L., Nussenzweig, Michel, Steinman, Ralph M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185598/
https://www.ncbi.nlm.nih.gov/pubmed/11062267

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