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CBA/N X-linked B-cell defect prevents NZB B-cell hyperactivity in F1 mice
NZB mice and their F1 hybrids produce excessive polyclonal IgM and autoantibodies of both IgM and IgG classes. CBA/N mice and CBA/N- mothered F1 males fail to make antibody to many T-independent antigens and have low levels of serum IgM; further, these mice lack a population of splenic B cells chara...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1979
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185603/ https://www.ncbi.nlm.nih.gov/pubmed/312908 |
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