Expression of endogenous xenotropic retrovirus by methylcholanthrene- induced squamous cell carcinoma of the mouse respiratory tract

As a model for human lung cancer, squamous cell carcinomas were induced by 3-methylcholanthrene in mouse tracheas which had been explanted to a subcutaneous site. The tumors that developed were examined for both ecotropic and xenotropic infectious murine leukemia virus (MuLV). From all squamous carc...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1979
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Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185731/
https://www.ncbi.nlm.nih.gov/pubmed/229191
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collection PubMed
description As a model for human lung cancer, squamous cell carcinomas were induced by 3-methylcholanthrene in mouse tracheas which had been explanted to a subcutaneous site. The tumors that developed were examined for both ecotropic and xenotropic infectious murine leukemia virus (MuLV). From all squamous carcinomas--six out of six--a xenotropic MuLV was isolated. From some of the fibrosarcomas that occurred incidentally in our induction system, ecotropic MuLV was isolated. However, in the fibrosarcomas, no xenotropic MuLV at all was found.
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spelling pubmed-21857312008-04-17 Expression of endogenous xenotropic retrovirus by methylcholanthrene- induced squamous cell carcinoma of the mouse respiratory tract J Exp Med Articles As a model for human lung cancer, squamous cell carcinomas were induced by 3-methylcholanthrene in mouse tracheas which had been explanted to a subcutaneous site. The tumors that developed were examined for both ecotropic and xenotropic infectious murine leukemia virus (MuLV). From all squamous carcinomas--six out of six--a xenotropic MuLV was isolated. From some of the fibrosarcomas that occurred incidentally in our induction system, ecotropic MuLV was isolated. However, in the fibrosarcomas, no xenotropic MuLV at all was found. The Rockefeller University Press 1979-12-01 /pmc/articles/PMC2185731/ /pubmed/229191 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Expression of endogenous xenotropic retrovirus by methylcholanthrene- induced squamous cell carcinoma of the mouse respiratory tract
title Expression of endogenous xenotropic retrovirus by methylcholanthrene- induced squamous cell carcinoma of the mouse respiratory tract
title_full Expression of endogenous xenotropic retrovirus by methylcholanthrene- induced squamous cell carcinoma of the mouse respiratory tract
title_fullStr Expression of endogenous xenotropic retrovirus by methylcholanthrene- induced squamous cell carcinoma of the mouse respiratory tract
title_full_unstemmed Expression of endogenous xenotropic retrovirus by methylcholanthrene- induced squamous cell carcinoma of the mouse respiratory tract
title_short Expression of endogenous xenotropic retrovirus by methylcholanthrene- induced squamous cell carcinoma of the mouse respiratory tract
title_sort expression of endogenous xenotropic retrovirus by methylcholanthrene- induced squamous cell carcinoma of the mouse respiratory tract
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185731/
https://www.ncbi.nlm.nih.gov/pubmed/229191

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