Acquisition of cell surface IgD after in vitro culture of neoplastic B cells from the murine tumor BCL1

Murine BCL1 tumor cells bear large amounts of surface IgM and trace amounts of surface IgD. In the present studies we have shown that cultivation of these cells, in the absence of lipopolysaccharide, results in the acquisition of IgD by virtually all the cells. These results suggest that BCL1 cells...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1980
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185800/
https://www.ncbi.nlm.nih.gov/pubmed/6987329
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description Murine BCL1 tumor cells bear large amounts of surface IgM and trace amounts of surface IgD. In the present studies we have shown that cultivation of these cells, in the absence of lipopolysaccharide, results in the acquisition of IgD by virtually all the cells. These results suggest that BCL1 cells can differentiate in vitro into more mature B cells and offer an attractive model for analyzing the factors controlling appearance of IgD on a monoclonal cell line.
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spelling pubmed-21858002008-04-17 Acquisition of cell surface IgD after in vitro culture of neoplastic B cells from the murine tumor BCL1 J Exp Med Articles Murine BCL1 tumor cells bear large amounts of surface IgM and trace amounts of surface IgD. In the present studies we have shown that cultivation of these cells, in the absence of lipopolysaccharide, results in the acquisition of IgD by virtually all the cells. These results suggest that BCL1 cells can differentiate in vitro into more mature B cells and offer an attractive model for analyzing the factors controlling appearance of IgD on a monoclonal cell line. The Rockefeller University Press 1980-03-01 /pmc/articles/PMC2185800/ /pubmed/6987329 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Acquisition of cell surface IgD after in vitro culture of neoplastic B cells from the murine tumor BCL1
title Acquisition of cell surface IgD after in vitro culture of neoplastic B cells from the murine tumor BCL1
title_full Acquisition of cell surface IgD after in vitro culture of neoplastic B cells from the murine tumor BCL1
title_fullStr Acquisition of cell surface IgD after in vitro culture of neoplastic B cells from the murine tumor BCL1
title_full_unstemmed Acquisition of cell surface IgD after in vitro culture of neoplastic B cells from the murine tumor BCL1
title_short Acquisition of cell surface IgD after in vitro culture of neoplastic B cells from the murine tumor BCL1
title_sort acquisition of cell surface igd after in vitro culture of neoplastic b cells from the murine tumor bcl1
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185800/
https://www.ncbi.nlm.nih.gov/pubmed/6987329

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