Murine pancreatic beta-cells express H-2K and H-2D but not Ia antigens

Direct microcytotoxicity testing and absorption analyses were employed to determine whether H-2K, H-2D, and Ia antigens are present on murine islet of Langerhans cells. Products of the H-2K and H-2D loci were found on beta-cells from three different mouse strains, but I-region (Ia) antigens were not...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1980
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185869/
https://www.ncbi.nlm.nih.gov/pubmed/6991630
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collection PubMed
description Direct microcytotoxicity testing and absorption analyses were employed to determine whether H-2K, H-2D, and Ia antigens are present on murine islet of Langerhans cells. Products of the H-2K and H-2D loci were found on beta-cells from three different mouse strains, but I-region (Ia) antigens were not detected. The absence of Ia gene products from islet cells may be of importance in explaining the survival of islet allografts across major histocompatibility barriers.
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spelling pubmed-21858692008-04-17 Murine pancreatic beta-cells express H-2K and H-2D but not Ia antigens J Exp Med Articles Direct microcytotoxicity testing and absorption analyses were employed to determine whether H-2K, H-2D, and Ia antigens are present on murine islet of Langerhans cells. Products of the H-2K and H-2D loci were found on beta-cells from three different mouse strains, but I-region (Ia) antigens were not detected. The absence of Ia gene products from islet cells may be of importance in explaining the survival of islet allografts across major histocompatibility barriers. The Rockefeller University Press 1980-06-01 /pmc/articles/PMC2185869/ /pubmed/6991630 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Murine pancreatic beta-cells express H-2K and H-2D but not Ia antigens
title Murine pancreatic beta-cells express H-2K and H-2D but not Ia antigens
title_full Murine pancreatic beta-cells express H-2K and H-2D but not Ia antigens
title_fullStr Murine pancreatic beta-cells express H-2K and H-2D but not Ia antigens
title_full_unstemmed Murine pancreatic beta-cells express H-2K and H-2D but not Ia antigens
title_short Murine pancreatic beta-cells express H-2K and H-2D but not Ia antigens
title_sort murine pancreatic beta-cells express h-2k and h-2d but not ia antigens
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185869/
https://www.ncbi.nlm.nih.gov/pubmed/6991630

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