Evidence that endogenous ecotropic virus is not expressed in AKR thymic lymphoid cells of chimeric hosts

AKR/J thymocytes derived from fetal liver cells do not produce virus when they differentiate in lethally irradiated B10.K mice, whereas spleen and bone marrow cells are virus producers. In contrast, B10.K thymocytes that differentiate in lethally irradiated AKR mice become virus producers. These res...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1980
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185939/
https://www.ncbi.nlm.nih.gov/pubmed/7400760
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collection PubMed
description AKR/J thymocytes derived from fetal liver cells do not produce virus when they differentiate in lethally irradiated B10.K mice, whereas spleen and bone marrow cells are virus producers. In contrast, B10.K thymocytes that differentiate in lethally irradiated AKR mice become virus producers. These results suggest that infection of the thymus in AKR mice is initiated in thymic stromal cells.
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spelling pubmed-21859392008-04-17 Evidence that endogenous ecotropic virus is not expressed in AKR thymic lymphoid cells of chimeric hosts J Exp Med Articles AKR/J thymocytes derived from fetal liver cells do not produce virus when they differentiate in lethally irradiated B10.K mice, whereas spleen and bone marrow cells are virus producers. In contrast, B10.K thymocytes that differentiate in lethally irradiated AKR mice become virus producers. These results suggest that infection of the thymus in AKR mice is initiated in thymic stromal cells. The Rockefeller University Press 1980-08-01 /pmc/articles/PMC2185939/ /pubmed/7400760 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Evidence that endogenous ecotropic virus is not expressed in AKR thymic lymphoid cells of chimeric hosts
title Evidence that endogenous ecotropic virus is not expressed in AKR thymic lymphoid cells of chimeric hosts
title_full Evidence that endogenous ecotropic virus is not expressed in AKR thymic lymphoid cells of chimeric hosts
title_fullStr Evidence that endogenous ecotropic virus is not expressed in AKR thymic lymphoid cells of chimeric hosts
title_full_unstemmed Evidence that endogenous ecotropic virus is not expressed in AKR thymic lymphoid cells of chimeric hosts
title_short Evidence that endogenous ecotropic virus is not expressed in AKR thymic lymphoid cells of chimeric hosts
title_sort evidence that endogenous ecotropic virus is not expressed in akr thymic lymphoid cells of chimeric hosts
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185939/
https://www.ncbi.nlm.nih.gov/pubmed/7400760

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