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Preparation, characterization, and immunogenicity of Haemophilus influenzae type b polysaccharide-protein conjugates
A method is presented for covalently bonding Haemophilus influenzae type b capsular polysaccharide (HIB Ps) to several proteins. The method is efficient and relies upon the use of adipic dihydrazide as a spacer between the capsular polysaccharide and the carrier protein. In contrast to the poor immu...
| Formato: | Texto |
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| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1980
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185954/ https://www.ncbi.nlm.nih.gov/pubmed/6967514 |