Cargando…
Relation of putative thioester bond in C3 to activation of the alternative pathway and the binding of C3b to biological targets of complement
The reaction of [14C]methylamine with native human C3 led to the stoichiometric incorporation of methylamine, loss of hemolytic activity, and the concomitant exposure of a sulfhydryl group that could be labeled with [14C]iodoacetamide. Both labeled sites were located in the C3d portion of the alpha-...
Formato: | Texto |
---|---|
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1980
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2185963/ https://www.ncbi.nlm.nih.gov/pubmed/6903192 |
Ejemplares similares
-
Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3
Publicado: (1981) -
THE C3-ACTIVATOR SYSTEM: AN ALTERNATE PATHWAY OF COMPLEMENT ACTIVATION
por: Götze, Otto, et al.
Publicado: (1971) -
Regulation of C3 Activation by the Alternative Complement Pathway in the Mouse Retina
por: Williams, Jennifer A. E., et al.
Publicado: (2016) -
The Sand Fly Salivary Protein Lufaxin Inhibits the Early Steps of the Alternative Pathway of Complement by Direct Binding to the Proconvertase C3b-B
por: Mendes-Sousa, Antonio F., et al.
Publicado: (2017) -
Alternative pathway of complement: recruitment of precursor properdin by the labile C3/C5 convertase and the potentiation of the pathway
Publicado: (1976)