Identification of a human T lymphocyte surface protein associated with the E-rosette receptor

We describe a new monoclonal murine antibody that reacts with a 50,000- mol wt polypeptide that appears to be present on all E-rosetting cells. We conclude that this antigen is either identical to or closely associated with the E receptor because of (a) the high degree of concordance between E-roset...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1981
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186049/
https://www.ncbi.nlm.nih.gov/pubmed/6969782
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description We describe a new monoclonal murine antibody that reacts with a 50,000- mol wt polypeptide that appears to be present on all E-rosetting cells. We conclude that this antigen is either identical to or closely associated with the E receptor because of (a) the high degree of concordance between E-rosette formation and 9.6 antigen expression, (b) the inhibition of rosette formation by preincubation of cells with 9.6 antibody, and (c) the observed failure of cells lysostripped of 9.6 antigen to form E-rosettes. This last finding suggests cocapping of 9.6 antigen and the E receptor.
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spelling pubmed-21860492008-04-17 Identification of a human T lymphocyte surface protein associated with the E-rosette receptor J Exp Med Articles We describe a new monoclonal murine antibody that reacts with a 50,000- mol wt polypeptide that appears to be present on all E-rosetting cells. We conclude that this antigen is either identical to or closely associated with the E receptor because of (a) the high degree of concordance between E-rosette formation and 9.6 antigen expression, (b) the inhibition of rosette formation by preincubation of cells with 9.6 antibody, and (c) the observed failure of cells lysostripped of 9.6 antigen to form E-rosettes. This last finding suggests cocapping of 9.6 antigen and the E receptor. The Rockefeller University Press 1981-01-01 /pmc/articles/PMC2186049/ /pubmed/6969782 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Identification of a human T lymphocyte surface protein associated with the E-rosette receptor
title Identification of a human T lymphocyte surface protein associated with the E-rosette receptor
title_full Identification of a human T lymphocyte surface protein associated with the E-rosette receptor
title_fullStr Identification of a human T lymphocyte surface protein associated with the E-rosette receptor
title_full_unstemmed Identification of a human T lymphocyte surface protein associated with the E-rosette receptor
title_short Identification of a human T lymphocyte surface protein associated with the E-rosette receptor
title_sort identification of a human t lymphocyte surface protein associated with the e-rosette receptor
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186049/
https://www.ncbi.nlm.nih.gov/pubmed/6969782

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