Induction of delayed-type hypersensitivity to azobenzenearsonate by a monoclonal anti-idiotype antibody

Azobenzenearsonate (ABA)-specific sensitivity was induced in A/J mice by injecting a monoclonal anti-idiotype reagent, 14A, directed against a determinant present on a minor subpopulation of immunoglobulin molecules within the anti-ABA antibodies of A/J mice. Sensitivity was transferrable by purifie...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1981
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186111/
https://www.ncbi.nlm.nih.gov/pubmed/6788881
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collection PubMed
description Azobenzenearsonate (ABA)-specific sensitivity was induced in A/J mice by injecting a monoclonal anti-idiotype reagent, 14A, directed against a determinant present on a minor subpopulation of immunoglobulin molecules within the anti-ABA antibodies of A/J mice. Sensitivity was transferrable by purified T cells and this was abrogated by treating the cells with 14A, rabbit anti-mouse immunoglobulin and complement, not by treatment with only the last two reagents. The transfer was restricted by the K-end of the major histocompatibility complex.
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spelling pubmed-21861112008-04-17 Induction of delayed-type hypersensitivity to azobenzenearsonate by a monoclonal anti-idiotype antibody J Exp Med Articles Azobenzenearsonate (ABA)-specific sensitivity was induced in A/J mice by injecting a monoclonal anti-idiotype reagent, 14A, directed against a determinant present on a minor subpopulation of immunoglobulin molecules within the anti-ABA antibodies of A/J mice. Sensitivity was transferrable by purified T cells and this was abrogated by treating the cells with 14A, rabbit anti-mouse immunoglobulin and complement, not by treatment with only the last two reagents. The transfer was restricted by the K-end of the major histocompatibility complex. The Rockefeller University Press 1981-03-01 /pmc/articles/PMC2186111/ /pubmed/6788881 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Induction of delayed-type hypersensitivity to azobenzenearsonate by a monoclonal anti-idiotype antibody
title Induction of delayed-type hypersensitivity to azobenzenearsonate by a monoclonal anti-idiotype antibody
title_full Induction of delayed-type hypersensitivity to azobenzenearsonate by a monoclonal anti-idiotype antibody
title_fullStr Induction of delayed-type hypersensitivity to azobenzenearsonate by a monoclonal anti-idiotype antibody
title_full_unstemmed Induction of delayed-type hypersensitivity to azobenzenearsonate by a monoclonal anti-idiotype antibody
title_short Induction of delayed-type hypersensitivity to azobenzenearsonate by a monoclonal anti-idiotype antibody
title_sort induction of delayed-type hypersensitivity to azobenzenearsonate by a monoclonal anti-idiotype antibody
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186111/
https://www.ncbi.nlm.nih.gov/pubmed/6788881

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