Adjuvant polyarthritis. V. Induction by N-acetylmuramyl-L-alanyl-D- isoglutamine, the smallest peptide subunit of bacterial peptidoglycan

N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP), an apparently nonimmunogenic bacterial peptidoglycan-derived small peptide, was found to induce a polyarthritis the rat similar to that induced by Freund's complete adjuvant when injected in the form of an oil emulsion. An oil emulsion of its isome...

Descripción completa

Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1981
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186125/
https://www.ncbi.nlm.nih.gov/pubmed/6972989
_version_ 1782145894800424960
collection PubMed
description N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP), an apparently nonimmunogenic bacterial peptidoglycan-derived small peptide, was found to induce a polyarthritis the rat similar to that induced by Freund's complete adjuvant when injected in the form of an oil emulsion. An oil emulsion of its isomer, N-acetylmuramyl-L-alanyl-L-isoglutamine, which unlike MDP has no immunostimulatory activity, failed to induce the disease.
format Text
id pubmed-2186125
institution National Center for Biotechnology Information
language English
publishDate 1981
publisher The Rockefeller University Press
record_format MEDLINE/PubMed
spelling pubmed-21861252008-04-17 Adjuvant polyarthritis. V. Induction by N-acetylmuramyl-L-alanyl-D- isoglutamine, the smallest peptide subunit of bacterial peptidoglycan J Exp Med Articles N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP), an apparently nonimmunogenic bacterial peptidoglycan-derived small peptide, was found to induce a polyarthritis the rat similar to that induced by Freund's complete adjuvant when injected in the form of an oil emulsion. An oil emulsion of its isomer, N-acetylmuramyl-L-alanyl-L-isoglutamine, which unlike MDP has no immunostimulatory activity, failed to induce the disease. The Rockefeller University Press 1981-04-01 /pmc/articles/PMC2186125/ /pubmed/6972989 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Adjuvant polyarthritis. V. Induction by N-acetylmuramyl-L-alanyl-D- isoglutamine, the smallest peptide subunit of bacterial peptidoglycan
title Adjuvant polyarthritis. V. Induction by N-acetylmuramyl-L-alanyl-D- isoglutamine, the smallest peptide subunit of bacterial peptidoglycan
title_full Adjuvant polyarthritis. V. Induction by N-acetylmuramyl-L-alanyl-D- isoglutamine, the smallest peptide subunit of bacterial peptidoglycan
title_fullStr Adjuvant polyarthritis. V. Induction by N-acetylmuramyl-L-alanyl-D- isoglutamine, the smallest peptide subunit of bacterial peptidoglycan
title_full_unstemmed Adjuvant polyarthritis. V. Induction by N-acetylmuramyl-L-alanyl-D- isoglutamine, the smallest peptide subunit of bacterial peptidoglycan
title_short Adjuvant polyarthritis. V. Induction by N-acetylmuramyl-L-alanyl-D- isoglutamine, the smallest peptide subunit of bacterial peptidoglycan
title_sort adjuvant polyarthritis. v. induction by n-acetylmuramyl-l-alanyl-d- isoglutamine, the smallest peptide subunit of bacterial peptidoglycan
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186125/
https://www.ncbi.nlm.nih.gov/pubmed/6972989

Ejemplares similares