Nucleic acid and protein sequences of phosphocholine-binding light chains

An 18-kilobase DNA fragment containing the sequence coding for both the variable and constant regions of the S107 mouse immunoglobulin light chain was cloned from total cellular DNA. The complete nucleotide sequence of the kappa-chain variable-region gene is reported. Determination of the amino acid...

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Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1981
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186162/
https://www.ncbi.nlm.nih.gov/pubmed/6788890
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collection PubMed
description An 18-kilobase DNA fragment containing the sequence coding for both the variable and constant regions of the S107 mouse immunoglobulin light chain was cloned from total cellular DNA. The complete nucleotide sequence of the kappa-chain variable-region gene is reported. Determination of the amino acid sequence encoded by the DNA is found to be identical to the protein sequence of the T15 light chain through residue 88. Direct sequence analysis confirmed that the J1 joining segment is used in the recombination event producing the active kappa light chain gene.
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spelling pubmed-21861622008-04-17 Nucleic acid and protein sequences of phosphocholine-binding light chains J Exp Med Articles An 18-kilobase DNA fragment containing the sequence coding for both the variable and constant regions of the S107 mouse immunoglobulin light chain was cloned from total cellular DNA. The complete nucleotide sequence of the kappa-chain variable-region gene is reported. Determination of the amino acid sequence encoded by the DNA is found to be identical to the protein sequence of the T15 light chain through residue 88. Direct sequence analysis confirmed that the J1 joining segment is used in the recombination event producing the active kappa light chain gene. The Rockefeller University Press 1981-05-01 /pmc/articles/PMC2186162/ /pubmed/6788890 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Nucleic acid and protein sequences of phosphocholine-binding light chains
title Nucleic acid and protein sequences of phosphocholine-binding light chains
title_full Nucleic acid and protein sequences of phosphocholine-binding light chains
title_fullStr Nucleic acid and protein sequences of phosphocholine-binding light chains
title_full_unstemmed Nucleic acid and protein sequences of phosphocholine-binding light chains
title_short Nucleic acid and protein sequences of phosphocholine-binding light chains
title_sort nucleic acid and protein sequences of phosphocholine-binding light chains
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186162/
https://www.ncbi.nlm.nih.gov/pubmed/6788890

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