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Primary non Hodgkin's lymphoma of the lacrimal sac
BACKGROUND: Primary Non Hodgkin's Lymphoma (NHL) of the lacrimal sac is rare. METHODS: The clinical features of a 78 year old female who presented with epiphora and swelling of the left lacrimal sac are described. RESULTS: Computerised tomography showed a mass involving the left lacrimal sac. H...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186337/ https://www.ncbi.nlm.nih.gov/pubmed/17986344 http://dx.doi.org/10.1186/1477-7819-5-127 |
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author | Venkitaraman, Ramachandran George, Mathew K |
author_facet | Venkitaraman, Ramachandran George, Mathew K |
author_sort | Venkitaraman, Ramachandran |
collection | PubMed |
description | BACKGROUND: Primary Non Hodgkin's Lymphoma (NHL) of the lacrimal sac is rare. METHODS: The clinical features of a 78 year old female who presented with epiphora and swelling of the left lacrimal sac are described. RESULTS: Computerised tomography showed a mass involving the left lacrimal sac. Histopathological examination revealed a diffuse large B cell NHL. Immunohistological examination demonstrated B cell origin. Chemotherapy could not be administered due to co morbid conditions. The patient was treated with radiotherapy to a dose of 45 Gy in 25 fractions. Patient is disease free and on follow up after 36 months. CONCLUSION: Primary radiotherapy is a treatment option with curative potential for localized NHL of the lacrimal sac and may be considered in patients who cannot tolerate appropriate chemotherapy. |
format | Text |
id | pubmed-2186337 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-21863372008-01-10 Primary non Hodgkin's lymphoma of the lacrimal sac Venkitaraman, Ramachandran George, Mathew K World J Surg Oncol Case Report BACKGROUND: Primary Non Hodgkin's Lymphoma (NHL) of the lacrimal sac is rare. METHODS: The clinical features of a 78 year old female who presented with epiphora and swelling of the left lacrimal sac are described. RESULTS: Computerised tomography showed a mass involving the left lacrimal sac. Histopathological examination revealed a diffuse large B cell NHL. Immunohistological examination demonstrated B cell origin. Chemotherapy could not be administered due to co morbid conditions. The patient was treated with radiotherapy to a dose of 45 Gy in 25 fractions. Patient is disease free and on follow up after 36 months. CONCLUSION: Primary radiotherapy is a treatment option with curative potential for localized NHL of the lacrimal sac and may be considered in patients who cannot tolerate appropriate chemotherapy. BioMed Central 2007-11-06 /pmc/articles/PMC2186337/ /pubmed/17986344 http://dx.doi.org/10.1186/1477-7819-5-127 Text en Copyright © 2007 Venkitaraman and George; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Venkitaraman, Ramachandran George, Mathew K Primary non Hodgkin's lymphoma of the lacrimal sac |
title | Primary non Hodgkin's lymphoma of the lacrimal sac |
title_full | Primary non Hodgkin's lymphoma of the lacrimal sac |
title_fullStr | Primary non Hodgkin's lymphoma of the lacrimal sac |
title_full_unstemmed | Primary non Hodgkin's lymphoma of the lacrimal sac |
title_short | Primary non Hodgkin's lymphoma of the lacrimal sac |
title_sort | primary non hodgkin's lymphoma of the lacrimal sac |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186337/ https://www.ncbi.nlm.nih.gov/pubmed/17986344 http://dx.doi.org/10.1186/1477-7819-5-127 |
work_keys_str_mv | AT venkitaramanramachandran primarynonhodgkinslymphomaofthelacrimalsac AT georgemathewk primarynonhodgkinslymphomaofthelacrimalsac |