Cargando…
Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma Cells
BACKGROUND: Hepatocellular carcinoma (HCC) is the most invasive and frequently diagnosed malignancy and the second leading cause of cancer death in many regions of Asia. The PI3K/Akt/mTOR signal pathway is involved in multiple cellular functions including proliferation, differentiation, tumorigenesi...
Autores principales: | Bu, Xinxin, Jia, Fengqi, Wang, Weifeng, Guo, Xianling, Wu, Mengchao, Wei, Lixin |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186345/ https://www.ncbi.nlm.nih.gov/pubmed/17996122 http://dx.doi.org/10.1186/1471-2407-7-208 |
Ejemplares similares
-
Telomerase and mTOR in the brain: the mitochondria connection
por: Miwa, Satomi, et al.
Publicado: (2017) -
Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition
por: Charette, Nicolas, et al.
Publicado: (2010) -
Loss of AIM2 expression promotes hepatocarcinoma progression through activation of mTOR-S6K1 pathway
por: Ma, Xiaomin, et al.
Publicado: (2016) -
Antitumor Efficacy of Huqizhengxiao (HQZX) Decoction Based on
Inhibition of Telomerase Activity in Nude Mice of Hepatocarcinoma
Xenograft
por: Yu, XiaoXiao, et al.
Publicado: (2018) -
Extract of Cycas revoluta Thunb. enhances the inhibitory effect of 5-fluorouracil on gastric cancer cells through the AKT-mTOR pathway
por: Cui, Xing-Liang, et al.
Publicado: (2019)