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Mechanism of action of the C4 nephritic factor. Deregulation of the classical pathway of C3 convertase
Three mechanisms that regulate the formation and function of the classical pathway C3 convertase (C4b2a) have been elucidated: (a) an intrinsic decay of the enzyme that is temperature dependent; (b) an extrinsic decay mediated by the effect of the serum protein C4b binding protein (C4-bp); and (c) i...
Formato: | Texto |
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Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1981
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186394/ https://www.ncbi.nlm.nih.gov/pubmed/7019379 |
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