Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1

Monoclonal antibodies have been obtained that react with the murine leukocyte surface glycoproteins bearing the macrophage differentiation antigen Mac-1. Structural and antigenic analysis shows that related glycoproteins are found on other murine hematopoietic cell types. The data not only illustrat...

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Detalles Bibliográficos
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1981
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186511/
https://www.ncbi.nlm.nih.gov/pubmed/7299345
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collection PubMed
description Monoclonal antibodies have been obtained that react with the murine leukocyte surface glycoproteins bearing the macrophage differentiation antigen Mac-1. Structural and antigenic analysis shows that related glycoproteins are found on other murine hematopoietic cell types. The data not only illustrate the complexity of cell surface structures that can be detected by means of monoclonal antibodies, but also raise questions as to the functional significance of this family of molecules within the hematopoietic system.
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spelling pubmed-21865112008-04-17 Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1 J Exp Med Articles Monoclonal antibodies have been obtained that react with the murine leukocyte surface glycoproteins bearing the macrophage differentiation antigen Mac-1. Structural and antigenic analysis shows that related glycoproteins are found on other murine hematopoietic cell types. The data not only illustrate the complexity of cell surface structures that can be detected by means of monoclonal antibodies, but also raise questions as to the functional significance of this family of molecules within the hematopoietic system. The Rockefeller University Press 1981-11-01 /pmc/articles/PMC2186511/ /pubmed/7299345 Text en This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Articles
Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1
title Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1
title_full Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1
title_fullStr Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1
title_full_unstemmed Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1
title_short Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1
title_sort molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen mac-1
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2186511/
https://www.ncbi.nlm.nih.gov/pubmed/7299345

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